Dataset | set02_ATM_minus_versus_BT_ATM_minus |
Phenotype | NoPhenotypeAvailable |
Upregulated in class | na_neg |
GeneSet | NCI_IL1-MEDIATED SIGNALING EVENTS |
Enrichment Score (ES) | -0.41298983 |
Normalized Enrichment Score (NES) | -1.8719213 |
Nominal p-value | 0.0 |
FDR q-value | 0.040406127 |
FWER p-Value | 0.459 |
PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|
1 | IL2RA | 15 | 4.747 | 0.0152 | No | ||
2 | NUP214 | 64 | 3.714 | 0.0254 | No | ||
3 | RPS6KA5 | 107 | 3.380 | 0.0348 | No | ||
4 | CREB1 | 126 | 3.257 | 0.0449 | No | ||
5 | LCK | 137 | 3.203 | 0.0551 | No | ||
6 | MAP2K6 | 175 | 2.990 | 0.0634 | No | ||
7 | ITCH | 197 | 2.938 | 0.0723 | No | ||
8 | CSNK2A1 | 381 | 2.459 | 0.0721 | No | ||
9 | PRKCA | 397 | 2.430 | 0.0795 | No | ||
10 | CASP3 | 413 | 2.406 | 0.0869 | No | ||
11 | ATF2 | 444 | 2.361 | 0.0934 | No | ||
12 | MAP3K7 | 448 | 2.353 | 0.1011 | No | ||
13 | CREBBP | 519 | 2.250 | 0.1055 | No | ||
14 | YWHAZ | 622 | 2.135 | 0.1079 | No | ||
15 | IL5 | 751 | 2.009 | 0.1087 | No | ||
16 | GSK3B | 765 | 1.997 | 0.1148 | No | ||
17 | PIK3CA | 824 | 1.937 | 0.1186 | No | ||
18 | PLA2G4A | 906 | 1.879 | 0.1212 | No | ||
19 | HBP1 | 986 | 1.830 | 0.1237 | No | ||
20 | TMED7 | 1099 | 1.758 | 0.1244 | No | ||
21 | EIF4E | 1119 | 1.747 | 0.1294 | No | ||
22 | CTLA4 | 1130 | 1.742 | 0.1348 | No | ||
23 | MAPK8 | 1169 | 1.724 | 0.1388 | No | ||
24 | MAP3K7IP1 | 1279 | 1.667 | 0.1394 | No | ||
25 | CAMK4 | 1351 | 1.628 | 0.1415 | No | ||
26 | SYK | 1418 | 1.598 | 0.1439 | No | ||
27 | RAB5A | 1531 | 1.549 | 0.1439 | No | ||
28 | YWHAE | 1550 | 1.540 | 0.1482 | No | ||
29 | TRAF6 | 1621 | 1.510 | 0.1501 | No | ||
30 | CSNK1A1 | 1654 | 1.498 | 0.1536 | No | ||
31 | ESR1 | 1688 | 1.488 | 0.1571 | No | ||
32 | PPARGC1A | 1723 | 1.472 | 0.1604 | No | ||
33 | MITF | 2097 | 1.330 | 0.1477 | No | ||
34 | PIK3R1 | 2157 | 1.312 | 0.1494 | No | ||
35 | CDC25B | 2332 | 1.248 | 0.1456 | No | ||
36 | PTPRK | 2458 | 1.209 | 0.1439 | No | ||
37 | PRKCE | 2610 | 1.173 | 0.1409 | No | ||
38 | POU2F1 | 2833 | 1.121 | 0.1344 | No | ||
39 | RAN | 3501 | 0.968 | 0.1070 | No | ||
40 | CEBPB | 3658 | 0.937 | 0.1030 | No | ||
41 | PIM1 | 3908 | 0.888 | 0.0945 | No | ||
42 | ERC1 | 3923 | 0.885 | 0.0968 | No | ||
43 | MEF2A | 3968 | 0.878 | 0.0977 | No | ||
44 | MALT1 | 4026 | 0.868 | 0.0980 | No | ||
45 | PAK3 | 4071 | 0.860 | 0.0989 | No | ||
46 | KPNB1 | 4321 | 0.818 | 0.0902 | No | ||
47 | MAP3K7IP2 | 4322 | 0.818 | 0.0929 | No | ||
48 | TH | 4459 | 0.792 | 0.0893 | No | ||
49 | BAD | 4507 | 0.786 | 0.0898 | No | ||
50 | UBE2D3 | 4979 | 0.711 | 0.0705 | No | ||
51 | EP300 | 5873 | 0.578 | 0.0314 | No | ||
52 | FASLG | 5895 | 0.575 | 0.0324 | No | ||
53 | NFATC3 | 5945 | 0.567 | 0.0320 | No | ||
54 | RALA | 5982 | 0.562 | 0.0322 | No | ||
55 | IL4 | 5986 | 0.560 | 0.0340 | No | ||
56 | CHUK | 6349 | 0.506 | 0.0190 | No | ||
57 | IRAK1 | 7424 | 0.365 | -0.0291 | No | ||
58 | E2F1 | 7467 | 0.357 | -0.0298 | No | ||
59 | XPO1 | 7628 | 0.335 | -0.0361 | No | ||
60 | CDK4 | 7918 | 0.298 | -0.0484 | No | ||
61 | FKBP8 | 8018 | 0.285 | -0.0519 | No | ||
62 | PPARG | 8381 | 0.235 | -0.0678 | No | ||
63 | FGR | 8504 | 0.217 | -0.0727 | No | ||
64 | MAP3K1 | 8906 | 0.161 | -0.0906 | No | ||
65 | ATF1 | 9205 | 0.120 | -0.1039 | No | ||
66 | TNFRSF1A | 9263 | 0.111 | -0.1061 | No | ||
67 | IL3 | 9524 | 0.071 | -0.1178 | No | ||
68 | CALM2 | 10266 | -0.045 | -0.1517 | No | ||
69 | EGR4 | 10291 | -0.048 | -0.1527 | No | ||
70 | CASP1 | 10532 | -0.083 | -0.1634 | No | ||
71 | AKAP5 | 10935 | -0.146 | -0.1814 | No | ||
72 | IL1A | 10944 | -0.147 | -0.1813 | No | ||
73 | RAF1 | 11386 | -0.204 | -0.2009 | No | ||
74 | PAK2 | 12116 | -0.285 | -0.2334 | No | ||
75 | DDIT3 | 12521 | -0.335 | -0.2509 | No | ||
76 | TBX21 | 12958 | -0.386 | -0.2696 | No | ||
77 | BLK | 13045 | -0.396 | -0.2722 | No | ||
78 | MAP3K8 | 13234 | -0.417 | -0.2795 | No | ||
79 | PRKCI | 13268 | -0.420 | -0.2796 | No | ||
80 | MAP2K3 | 13472 | -0.447 | -0.2874 | No | ||
81 | IL1R1 | 13480 | -0.449 | -0.2862 | No | ||
82 | DUSP16 | 13526 | -0.454 | -0.2868 | No | ||
83 | SRC | 13765 | -0.482 | -0.2961 | No | ||
84 | ELK4 | 13831 | -0.491 | -0.2974 | No | ||
85 | USF1 | 13855 | -0.493 | -0.2969 | No | ||
86 | CCM2 | 13964 | -0.505 | -0.3001 | No | ||
87 | BIRC2 | 14071 | -0.516 | -0.3033 | No | ||
88 | RNF128 | 14244 | -0.538 | -0.3094 | No | ||
89 | CSF2 | 14405 | -0.557 | -0.3149 | No | ||
90 | REL | 14487 | -0.568 | -0.3167 | No | ||
91 | YES1 | 14598 | -0.581 | -0.3198 | No | ||
92 | MAP2K4 | 14640 | -0.588 | -0.3197 | No | ||
93 | IL1B | 14865 | -0.614 | -0.3280 | No | ||
94 | HSPB1 | 15001 | -0.628 | -0.3321 | No | ||
95 | YWHAQ | 15062 | -0.634 | -0.3327 | No | ||
96 | CALM1 | 15082 | -0.637 | -0.3314 | No | ||
97 | IFNG | 15303 | -0.665 | -0.3393 | No | ||
98 | UBE2N | 15327 | -0.668 | -0.3381 | No | ||
99 | MAPK3 | 15401 | -0.677 | -0.3392 | No | ||
100 | RIPK2 | 15580 | -0.698 | -0.3451 | No | ||
101 | TSC2 | 15645 | -0.708 | -0.3456 | No | ||
102 | EIF4EBP1 | 15826 | -0.732 | -0.3515 | No | ||
103 | FOSL1 | 16325 | -0.800 | -0.3717 | No | ||
104 | CD40LG | 16375 | -0.807 | -0.3712 | No | ||
105 | MAPKAPK2 | 16390 | -0.809 | -0.3692 | No | ||
106 | NFKBIA | 16391 | -0.809 | -0.3665 | No | ||
107 | HCK | 16436 | -0.815 | -0.3658 | No | ||
108 | YWHAB | 16464 | -0.818 | -0.3643 | No | ||
109 | SLC9A1 | 16483 | -0.821 | -0.3623 | No | ||
110 | PAK1 | 16504 | -0.823 | -0.3605 | No | ||
111 | IRAK4 | 16616 | -0.837 | -0.3628 | No | ||
112 | DUSP8 | 16645 | -0.841 | -0.3613 | No | ||
113 | MAP3K14 | 16757 | -0.855 | -0.3635 | No | ||
114 | RIPK1 | 16874 | -0.871 | -0.3659 | No | ||
115 | PTGS2 | 17046 | -0.900 | -0.3708 | No | ||
116 | GATA3 | 17055 | -0.902 | -0.3681 | No | ||
117 | MYD88 | 17441 | -0.960 | -0.3826 | No | ||
118 | MAPK9 | 17448 | -0.962 | -0.3797 | No | ||
119 | ETV1 | 17507 | -0.973 | -0.3791 | No | ||
120 | RELA | 17566 | -0.984 | -0.3785 | No | ||
121 | IL1R2 | 17621 | -0.994 | -0.3776 | No | ||
122 | PRKACA | 17631 | -0.996 | -0.3747 | No | ||
123 | YWHAH | 17687 | -1.006 | -0.3739 | No | ||
124 | IL1RN | 18058 | -1.069 | -0.3873 | No | ||
125 | DGKA | 18084 | -1.073 | -0.3848 | No | ||
126 | JUN | 18099 | -1.076 | -0.3819 | No | ||
127 | RPS6KA4 | 18117 | -1.078 | -0.3791 | No | ||
128 | MKNK1 | 18366 | -1.127 | -0.3867 | No | ||
129 | BCL2 | 18625 | -1.179 | -0.3946 | No | ||
130 | ATM | 18685 | -1.190 | -0.3933 | No | ||
131 | IKBKG | 18928 | -1.246 | -0.4003 | No | ||
132 | CYLD | 18965 | -1.255 | -0.3977 | No | ||
133 | PRKCQ | 19298 | -1.339 | -0.4085 | Yes | ||
134 | TNF | 19341 | -1.351 | -0.4059 | Yes | ||
135 | RAC1 | 19377 | -1.360 | -0.4030 | Yes | ||
136 | CALM3 | 19591 | -1.421 | -0.4080 | Yes | ||
137 | TP53 | 19687 | -1.455 | -0.4075 | Yes | ||
138 | TNFAIP3 | 19726 | -1.471 | -0.4043 | Yes | ||
139 | SQSTM1 | 19798 | -1.497 | -0.4026 | Yes | ||
140 | FKBP1A | 19825 | -1.506 | -0.3988 | Yes | ||
141 | IRAK3 | 19914 | -1.534 | -0.3977 | Yes | ||
142 | SFN | 20083 | -1.603 | -0.4000 | Yes | ||
143 | FYN | 20107 | -1.612 | -0.3957 | Yes | ||
144 | IKBKB | 20132 | -1.623 | -0.3914 | Yes | ||
145 | MEF2C | 20238 | -1.670 | -0.3906 | Yes | ||
146 | PRKCZ | 20308 | -1.703 | -0.3881 | Yes | ||
147 | SLC3A2 | 20423 | -1.750 | -0.3875 | Yes | ||
148 | TOLLIP | 20513 | -1.805 | -0.3855 | Yes | ||
149 | PRKCD | 20514 | -1.805 | -0.3795 | Yes | ||
150 | SRF | 20535 | -1.816 | -0.3743 | Yes | ||
151 | MAF | 20636 | -1.867 | -0.3727 | Yes | ||
152 | PRKG1 | 20704 | -1.910 | -0.3694 | Yes | ||
153 | DUSP10 | 20732 | -1.927 | -0.3642 | Yes | ||
154 | LSP1 | 20764 | -1.943 | -0.3591 | Yes | ||
155 | PTPN1 | 20769 | -1.947 | -0.3527 | Yes | ||
156 | RALB | 20823 | -1.981 | -0.3486 | Yes | ||
157 | MAP3K12 | 20842 | -1.995 | -0.3427 | Yes | ||
158 | MEF2D | 20891 | -2.028 | -0.3381 | Yes | ||
159 | GDI1 | 20903 | -2.033 | -0.3318 | Yes | ||
160 | ATF6 | 20914 | -2.044 | -0.3255 | Yes | ||
161 | NFKB1 | 20944 | -2.065 | -0.3199 | Yes | ||
162 | MAPKAPK5 | 20969 | -2.083 | -0.3140 | Yes | ||
163 | FBXW11 | 20996 | -2.114 | -0.3081 | Yes | ||
164 | MAPK14 | 21120 | -2.209 | -0.3064 | Yes | ||
165 | DUSP1 | 21121 | -2.210 | -0.2990 | Yes | ||
166 | BCL10 | 21159 | -2.247 | -0.2932 | Yes | ||
167 | ARRB2 | 21227 | -2.318 | -0.2885 | Yes | ||
168 | FOXP3 | 21314 | -2.435 | -0.2843 | Yes | ||
169 | MAPKAPK3 | 21325 | -2.455 | -0.2766 | Yes | ||
170 | JUNB | 21440 | -2.670 | -0.2729 | Yes | ||
171 | CBLB | 21453 | -2.694 | -0.2644 | Yes | ||
172 | TCF3 | 21468 | -2.726 | -0.2559 | Yes | ||
173 | MAP3K3 | 21546 | -2.891 | -0.2498 | Yes | ||
174 | NFKB2 | 21615 | -3.137 | -0.2424 | Yes | ||
175 | YWHAG | 21678 | -3.403 | -0.2339 | Yes | ||
176 | PRKCH | 21736 | -3.724 | -0.2241 | Yes | ||
177 | NFATC2 | 21737 | -3.736 | -0.2116 | Yes | ||
178 | RELB | 21749 | -3.826 | -0.1993 | Yes | ||
179 | MAPK11 | 21793 | -4.191 | -0.1872 | Yes | ||
180 | IRF4 | 21795 | -4.216 | -0.1732 | Yes | ||
181 | BCL3 | 21865 | -4.977 | -0.1597 | Yes | ||
182 | NFATC1 | 21871 | -5.174 | -0.1426 | Yes | ||
183 | FOS | 21917 | -6.478 | -0.1230 | Yes | ||
184 | NR4A1 | 21923 | -6.633 | -0.1010 | Yes | ||
185 | EGR1 | 21942 | -8.847 | -0.0723 | Yes | ||
186 | EGR3 | 21943 | -9.744 | -0.0397 | Yes | ||
187 | EGR2 | 21944 | -11.902 | 0.0001 | Yes |